Description
Cagrilintide is a synthetic peptide modeled on amylin, the islet hormone co-secreted with insulin. The sequence is engineered with a fatty-acid side chain (acylation), a modification that promotes binding to serum proteins and slows enzymatic breakdown, giving the molecule a longer-lasting profile than the native peptide in experimental systems.
Because amylin signals through the calcitonin receptor in combination with receptor-activity-modifying proteins (RAMPs), Cagrilintide is of interest to laboratories studying amylin and calcitonin receptor pharmacology, ligand-receptor binding behavior, and downstream signaling. It also serves as a model compound for researchers examining how lipidation strategies influence peptide half-life and stability in vitro.
Bolt Peptide provides Cagrilintide as a lyophilized solid in a sealed glass vial, intended for reconstitution under controlled laboratory conditions by trained personnel.
- Amylin and calcitonin receptor (with RAMP) binding and signaling studies
- Structure-activity and receptor pharmacology investigations
- Peptide stability, acylation, and half-life extension research
- Assay development and analytical method reference work
Each batch is characterized for identity and purity by HPLC and mass spectrometry, with a lot-specific Certificate of Analysis (COA) available on request. For best stability, store the sealed vial cold and protected from light, and keep the lyophilized material dry until reconstitution.
Research Use Only: This material is supplied strictly for laboratory research. Not for human or animal consumption. It is not a drug, food, supplement, or cosmetic and has not been approved by the FDA.


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