Description
Ipamorelin is a five-residue synthetic peptide (Aib-His-D-2-Nal-D-Phe-Lys-NH₂) categorized within the growth hormone secretagogue (GHS) family. With a molecular weight of roughly 711 Da, it was first designed as a tool compound for probing the ghrelin receptor (GHS-R1a) and the cellular biology of the anterior pituitary.
This peptide is frequently cited for its highly selective receptor engagement, a property that sets it apart from several earlier secretagogue compounds and makes it a useful reference molecule in comparative receptor and signaling studies. Bolt Peptide offers it as a lyophilized powder for reconstitution in the laboratory.
Reported areas of investigation in the published literature include:
- GHS-R1a receptor pharmacology, including binding kinetics and downstream signal transduction
- Anterior pituitary cell models and their response to synthetic secretagogue peptides
- Comparative work contrasting native ghrelin with synthetic GHS analogs at the receptor level
- Receptor selectivity profiling relative to other peptide secretagogues
- Structure-activity studies on how pentapeptide modifications influence receptor affinity
Each vial contains 10mg of lyophilized Ipamorelin. Material is assessed for identity and purity by HPLC and mass spectrometry, with a Certificate of Analysis available on request. Store the sealed vial cold and protected from light, and reconstitute only under appropriate laboratory conditions.
Research Use Only: This material is supplied strictly for laboratory research. Not for human or animal consumption. It is not a drug, food, supplement, or cosmetic and has not been approved by the FDA.


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