PT-141 (10mg vials)

Description

PT-141 is a synthetic cyclic peptide built around the core of alpha-melanocyte-stimulating hormone (α-MSH). Carrying the sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH and a molecular weight near 1025 Da, it belongs to the melanocortin family of analogs and shares a close structural relationship with Melanotan II, differing primarily at the C-terminal residue.

As a member of the melanocortin class, PT-141 is studied for its interaction with melanocortin receptors. This places it within the broader landscape of receptor pharmacology investigations, where researchers examine how cyclic α-MSH-derived peptides engage their molecular targets and how sequence modifications influence binding characteristics.

The cyclic, constrained architecture of PT-141 also makes it a useful reference compound in structure-activity and peptide-chemistry work, where the relationship between ring conformation, amino acid substitutions, and receptor selectivity is of ongoing interest.

• Melanocortin receptor pharmacology and binding studies
• Structure-activity comparisons across α-MSH analogs
• Peptide chemistry and synthetic-analog characterization
• In vitro and cell-based melanocortin signaling models

Each vial from Bolt Peptide contains 10mg of lyophilized PT-141 and is verified for identity and purity (typically 99%+) by HPLC and mass spectrometry. A certificate of analysis is available on request. Store sealed vials cold and away from light, and reconstitute under appropriate laboratory conditions for handling research-grade peptides.

Research Use Only: This material is supplied strictly for laboratory research. Not for human or animal consumption. It is not a drug, food, supplement, or cosmetic and has not been approved by the FDA.