Description
Tesamorelin is a synthetic 44-amino-acid peptide modeled on human growth hormone-releasing hormone (GHRH). It carries a trans-3-hexenoic acid group attached at the N-terminus, a structural addition that improves the molecule’s resistance to enzymatic breakdown and gives it greater stability than the unmodified native sequence. First characterized under the development designation TH9507, the peptide has accumulated a broad body of biochemical and cell-based research literature.
From a mechanistic standpoint, Tesamorelin belongs to the family of GHRH analogs that engage the GHRH receptor on anterior pituitary cells. This interaction makes it a useful tool compound for examining receptor binding behavior, signal transduction, and the engineered modifications that extend a signaling peptide’s functional lifetime relative to its naturally occurring counterpart.
Researchers have referenced Tesamorelin across several non-clinical investigative areas, including:
- GHRH receptor pharmacology, including binding kinetics and downstream signaling pathways
- Anterior pituitary cell biology and responsiveness to modified GHRH analogs
- Peptide stability engineering and the influence of N-terminal modification on half-life and degradation resistance
- Structure-activity comparisons between the modified analog and the native GHRH sequence
Each unit from Bolt Peptide contains 10mg of lyophilized Tesamorelin sealed in a glass vial. Material is characterized for identity and purity by HPLC and mass spectrometry, and a corresponding certificate of analysis (COA) is available. For accurate experimental results, store the lyophilized powder cold and protected from light, reconstitute with an appropriate solvent, and handle using standard laboratory practice.
Research Use Only: This material is supplied strictly for laboratory research. Not for human or animal consumption. It is not a drug, food, supplement, or cosmetic and has not been approved by the FDA.


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