Adipotide, also called FTPP or the prohibitin-targeting peptide (Prohibitin-TP01), is an experimental peptidomimetic studied in animal models for its targeting of the vasculature supplying white adipose tissue. It links a homing peptide to a pro-apoptotic sequence, so the molecule is directed toward fat-tissue blood vessels where it triggers programmed cell death of the endothelial cells. […]
Author: Bolt Peptide
GHRP-2 vs GHRP-6: What Is the Difference? (Research Overview)
Both GHRP-2 and GHRP-6 are synthetic growth-hormone-releasing peptides (GHRPs) that act as agonists at the ghrelin receptor (GHS-R1a). The key difference studied in the lab is that GHRP-6 is associated with stronger appetite-stimulating (ghrelin-like) signaling in animal models, while GHRP-2 is often characterized as a more potent growth-hormone (GH) secretagogue relative to its other effects. […]
What Is Thymalin? A Thymic Peptide Bioregulator Overview
Thymalin is a peptide preparation derived from the thymus gland that is studied in immunological and “peptide bioregulator” research. It is associated with the Khavinson line of research on tissue-derived peptide complexes and has been investigated for effects on immune-cell regulation and thymic function in laboratory and clinical-research settings. This article is educational only. Thymalin […]
What Is LL-37? A Cathelicidin Antimicrobial Peptide Overview
LL-37 is the only human cathelicidin-derived antimicrobial peptide — a 37-amino-acid cationic, amphipathic peptide cleaved from the hCAP18 precursor protein. It is one of the most extensively studied host-defense peptides in laboratory research, where it is investigated for antimicrobial, immunomodulatory, and innate-immunity signaling activity. Research-use-only (RUO) note: LL-37 is referenced here strictly as a subject […]
What Is MGF (Mechano Growth Factor) and PEG-MGF?
MGF (Mechano Growth Factor) is a splice variant of insulin-like growth factor 1 — specifically the IGF-1Ec isoform — that is expressed in mechanically loaded or damaged muscle and is studied as a local tissue-repair factor in muscle-research models. PEG-MGF is a pegylated form of the peptide, engineered to improve stability and extend half-life for […]
What Is MK-677 (Ibutamoren)? A Research Overview
MK-677, also called ibutamoren, is an orally-active, non-peptide growth-hormone secretagogue that mimics the hormone ghrelin at the GHS-R1a (ghrelin) receptor. It has been studied in the scientific literature as a long-acting stimulator of the growth-hormone (GH) / insulin-like growth factor-1 (IGF-1) axis. Importantly, MK-677 is a synthetic small molecule — it is not a peptide, […]
What Is SS-31 (Elamipretide / MTP-131)? A Research Guide
SS-31, also known as elamipretide (and formerly MTP-131), is a synthetic mitochondria-targeting tetrapeptide that selectively binds cardiolipin on the inner mitochondrial membrane. It is studied in preclinical and clinical research focused on mitochondrial bioenergetics, oxidative stress, and cellular energy production. This article is educational only. Any research material referenced here is intended for research use […]
What Is Follistatin? A Myostatin-Pathway Research Overview
Follistatin is a naturally occurring secreted glycoprotein that binds and inhibits several members of the transforming growth factor beta (TGF-β) superfamily — most notably myostatin (GDF-8) and activin — and is studied as a negative regulator of these signaling pathways in muscle and tissue biology. Follistatin-344 (FS-344) is a commonly studied isoform/variant used in preclinical […]
What Is HGH Fragment 176-191? A Research Overview
HGH Fragment 176-191 is a synthetic peptide corresponding to amino acids 176–191 at the C-terminus of human growth hormone (GH). It is studied in lipid-metabolism research as the region of the GH molecule associated with fat metabolism, and in preclinical models it has been reported to influence lipolysis without the growth-promoting or IGF-1 effects of […]
What Is Gonadorelin? GnRH Decapeptide & the HPG Axis
Gonadorelin is a synthetic form of gonadotropin-releasing hormone (GnRH) — a decapeptide that acts on the GnRH receptor (GnRHR) on anterior-pituitary gonadotroph cells to stimulate the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). It is studied in reproductive endocrinology as a tool for probing the hypothalamic–pituitary–gonadal (HPG) axis. This article is educational only. […]
